NEURODEVO
The NEURODEVO group focuses its research activity on three main lines:
- Use of fish as models for screening molecules of interest for pharmaceutical, biotechnological, and biomedical applications.
- Use of fish as models for nervous system diseases. Nervous system regeneration in fish.
- Use of fish as research models in evolutionary and ecological developmental biology (eco-evo-devo). Study of the development and evolution of the central nervous system: morphogenesis, comparative genoarchitecture, and neurogenesis.
Address:
CIBUS Building-Floor 3, Rúa Lope Gómez de Marzoa s/n, Campus Vida, 15782, Santiago de Compostela, A Coruña
Coordinator
Components
Investigation lines
- Fish as models for the screen of molecules of interest for pharmaceutical, biotecnological and biomedical applications.
- Fish as models of nerovus system disease. Regeneration of the fish nervous system.
- Fish as models in evolutionary and ecological developmental biology of the central nervous system: genoarquitecture, morphogenesis and neurogenesis.
Relevant projects
- In vivo drug screen to identify new signalling pathways regulating spinal cord neurogenesis: role of prostanoids. Agencia Estatal de Investigación, Ministerio de Ciencia e Innovación (PID2020-115121GB-I00). IPs: Antón Barreiro Iglesias and Laura Elena Sánchez Piñón. Duración: 3 años (01/09/2021-31/08/2024). Financiación: 102850 euros.
- Grupo de Referencia competitiva NEURODEVO (GI-1853). Xunta de Galicia (ED431C 2021/18). Ayudas para la consolidación y estructuración de unidades de investigación competitivas y otras acciones de fomento en las universidades del Sistema universitario de Galicia, modalidad A: Grupos de referencia competitiva. IP (coordinator): Eva Candal Suárez. Duración: 2021-2024. Financiación: 200.000 €.
- Descodificacion de las bases moleculares de la neurogenesis en el adulto mediante el analisis de la dinamica transcripcional de nichos neurogenicos de larga duracion. MICINN 2017 (BFU2017-89861-P). IPs: Eva Candal Suárez e Isabel Rodríguez-Moldes Rey (USC). Duración: 2018-2020. Financiación: 133.100 €.
Relevant publications
- González-Llera L, Sobrido-Cameán D, Quelle-Regaldie A, Sánchez L, Barreiro-Iglesias A. An in vivo drug screen in zebrafish reveals that cyclooxygenase 2-derived prostaglandin D2 promotes spinal cord neurogenesis. Cell Prolif. 2024 May;57(5):e13594. doi: 10.1111/cpr.13594.
- Hernández-Núñez I, Robledo D, Mayeur H, Mazan S, Sánchez L, Adrio F, Barreiro-Iglesias A, Candal E. Loss of Active Neurogenesis in the Adult Shark Retina. Front Cell Dev Biol. 2021; 9:628721. doi: 10.3389/fcell.2021.628721.
- González-Llera L, Santos-Durán GN, Sobrido-Cameán D, Núñez-González C, Pérez-Fernández J, Barreiro-Iglesias A. Spontaneous regeneration of cholecystokinergic reticulospinal axons after a complete spinal cord injury in sea lampreys. Comput Struct Biotechnol J. 2024; 23:347-357. doi: 10.1016/j.csbj.2023.12.014.
- Rodríguez-Moldes I, Quintana-Urzainqui I, Santos-Durán GN, Ferreiro-Galve S, Pereira-Guldrís S, Candás M, Mazan S, Candal E. Identifying Amygdala-Like Territories in Scyliorhinus canicula (Chondrichthyan): Evidence for a Pallial Amygdala. Brain Behav Evol. 2022; 96(4-6):283-304. doi: 10.1159/000519221.
- Vidal-Vázquez N, Hernández-Núñez I, Carballo-Pacolet P, Salisbury S, Villamayor PR, Hervas-Sotomayor F, Yuan X, Lamanna F, Schneider C, Schmidt J, Mazan S, Kaessmann H, Adrio F, Robledo D, Barreiro-Iglesias A, Candal E. Single-nucleus RNA sequencing atlas of the postnatal retina of the shark Scyliorhinus canicula. bioRxiv 2024.04.12.589211.
